Jeannette Doeller PhD
Education: Received PhD in Biological
Sciences from Clemson University, 1986, dissertation advisor James Colacino,
dissertation title: A Study of the Gill Hemoglobin in the Nearly Gutless
Bivalve, Solemya velum Say (Protobranchia).
Academic Positions: Postdoctoral
Fellow with the American Heart Association, New York Affiliate, Albert Einstein
College of Medicine, Department of Physiology and Biophysics, 1986-1990,
postdoctoral advisor Beatrice Wittenberg. Fulbright Fellow, Innsbruck
University, Department of Zoology, 1990, advisor Erich Gnaiger. Research
Assistant and Associate Professor, UAB Department of Biology, 1992-2002.
Associate Dean, UAB Graduate School, 2002-2005. Director of the NSF-funded UAB
ADVANCE Institutional Transformation award, 2003-2005. Research Associate
Professor, UAB Department of Environmental Health Sciences, 8/2005-present.
Hydrogen sulfide is a respiratory toxin naturally and artificially produced in a number of environments. However, it also serves a critical energetic function in prokaryotes and some marine invertebrates. It has recently been shown to be produced in numerous mammalian cells under physiological conditions, and is now thought to play a protective role against oxidative stress and other pathologies. Work in our laboratory is currently focused on the protective role of sulfide in vascular and hepatic physiology, using real-time measurements of hydrogen sulfide in conjunction with functional assays of intact tissues, cells and isolated mitochondria.