Office of Energetics

Past Personnel

Peng Li, Ph.D.

Staff Statistician
Office: LHL 404
Phone: (205) 975-9153
Current Location

I joined the Office of Energetics in September of 2014. Presently, I am helping other investigators on the statistical issues in obesity-related research.

Under the mentorship of Dr. David Redden, I received my PhD in Biostatistics in 2014 from the University of Alabama at Birmingham (UAB), focusing on the small sample inferences of cluster randomized trials. I also hold a master degree in Computer Science from UAB as well as master and bachelor degrees in biochemistry from Wuhan University in China.


  1. Li P, Redden DT. Small sample performance of bias-corrected sandwich estimators for cluster-randomized trials with binary outcomes. Submitted to Statistics in Medicine, under the third review.
  2. Li P, Redden DT. Comparison of denominator degrees of freedom approximations on small sample performance of generalized linear mixed model in analyzing cluster-randomized trials. In preparation.
  3. Li P, Tiwari HK, Lin WY, Allison DB, Chung WK, Leibel RL, Yi N, Liu N. Genetic association analysis of 30 genes related to obesity in a European American population. Int J Obes (Lond). 2014 May; 38(5):724-9. doi: 10.1038/ijo.2013.140. PMID: 23900445
  4. Zhao X, Zhang W, Xing D, Li P, Fu J, Gong K, Hage FG, Oparil S, Chen YF. Endothelial cells overexpressing IL-8 receptor reduce cardiac remodeling and dysfunction following myocardial infarction. Am J Physiol Heart Circ Physiol. 2013 Aug; 305(4):H590-8. doi: 10.1152/ajpheart.00571.2012. PMID:23771691
  5. Xing D, Li P (Co-first author), Gong K, Yang Z, Yu H, Hage FG, Oparil S, Chen YF. Endothelial cells overexpressing interleukin-8 receptors reduce inflammatory and neointimal responses to arterial injury.Circulation. 2012 Mar 27; 125(12):1533-41. doi: 10.1161/CIRCULATIONAHA.111.078436. PMID: 22361324
  6. Gong K, Xing D, Li P, Aksut B, Ambalavanan N, Yang Q, Nozell SE, Oparil S, Chen YF. Hypoxia induces downregulation of PPAR-γ in isolated pulmonary arterial smooth muscle cells and in rat lung via transforming growth factor-β signaling. Am J Physiol Lung Cell Mol Physiol. 2011 Dec; 301(6):L899-907. doi: 10.1152/ajplung.00062.2011. PMID: 21926264
  7. Gong K, Xing D, Li P, Hilgers RH, Hage FG, Oparil S, Chen YF. cGMP inhibits TGF-beta signaling by sequestering Smad3 with cytosolic beta2-tubulin in pulmonary artery smooth muscle cells. Mol Endocrinol. 2011 Oct; 25(10):1794-803.  doi: 10.1210/me.2011-1009. PMID: 21868450
  8. Gong K, Chen YF, Li P, Lucas JA, Hage FG, Yang Q, Nozell SE, Oparil S, Xing D. Transforming growth factor-β inhibits myocardial PPARγ expression in pressure overload-induced cardiac fibrosis and remodeling in mice. J Hypertens. 2011 Sep; 29(9):1810-9.  doi: 10.1097/HJH.0b013e32834a4d03. PMID:21836474
  9. Lucas JA, Zhang Y, Li P, Gong K, Miller AP, Hassan E, Hage F, Xing D, Wells B, Oparil S, Chen YF. Inhibition of transforming growth factor-beta signaling induces left ventricular dilation and dysfunction in the pressure-overloaded heart. Am J Physiol Heart Circ Physiol. 2010 Feb; 298(2):H424-32. doi: 10.1152/ajpheart.00529.2009. PMID:19933419
  10. Ambalavanan N, Nicola T, Li P, Bulger A, Murphy-Ullrich J, Oparil S, Chen YF. Role of matrix metalloproteinase-2 in newborn mouse lungs under hypoxic conditions. Pediatr Res. 2008 Jan; 63(1):26-32. doi:10.1203/PDR.0b013e31815b690d. PMID:18043506
  11. Li P, Wang D, Lucas J, Oparil S, Xing D, Cao X, Novak L, Renfrow MB, Chen YF. Atrial natriuretic peptide inhibits transforming growth factor beta-induced Smad signaling and myofibroblast transformation in mouse cardiac fibroblasts. Circ Res. 2008 Feb 1; 102(2):185-192.  doi: 10.1161/​CIRCRESAHA.107.157677. PMID: 17991884
  12. Ambalavanan N, Li P, Bulger A, Murphy-Ullrich J, Oparil S, Chen YF. Endothelin-1 mediates hypoxia-induced increases in vascular collagen in the newborn mouse lung. Pediatr Res. 2007 May; 61(5 Pt 1):559-64. doi:10.1203/pdr.0b013e318045beae. PMID:17413856
  13. Li P, Oparil S, Novak L, Cao X, Shi W, Lucas J, Chen YF. ANP signaling inhibits TGF-beta-induced Smad2 and Smad3 nuclear translocation and extracellular matrix expression in rat pulmonary arterial smooth muscle cells. J Appl Physiol. 2007 Jan; 102(1):390-8.  doi: 10.1152/japplphysiol.00468.2006.  PMID:17038494
  14. Franco V, Chen YF, Feng JA, Li P, Wang D, Hasan E, Oparil S, Perry GJ. Eplerenone prevents adverse cardiac remodelling induced by pressure overload in atrial natriuretic peptide-null mice. Clin Exp Pharmacol Physiol. 2006 ep; 33(9):773-9.  doi: 10.1111/j.1440-1681.2006.04434.x.  PMID:16922805
  15. Chen YF, Feng JA, Li P, Xing D, Ambalavanan N, Oparil S. Atrial natriuretic peptide-dependent modulation of hypoxia-induced pulmonary vascular remodeling. Life Sci. 2006 Aug 29; 79(14):1357-65.  doi:  PMID:16714036
  16. Chen YF, Feng JA, Li P, Xing D, Zhang Y, Serra R, Ambalavanan N, Majid-Hassan E, Oparil S. Dominant negative mutation of the TGF-beta receptor blocks hypoxia-induced pulmonary vascular remodeling. J Appl Physiol. 2006 Feb; 100(2):564-71.  doi: 10.1152/japplphysiol.00595.2005. PMID:16223981
  17. Li P, Oparil S, Feng W, Chen YF. Hypoxia-responsive growth factors upregulate periostin and osteopontin expression via distinct signaling pathways in rat pulmonary arterial smooth muscle cells. J Appl Physiol. 2004 Oct; 97(4):1550-8; discussion 1549.  doi: 10.1152/japplphysiol.01311.2003.  PMID:15121739
  18. Li P, Oparil S, Sun JZ, Thompson JA, Chen YF. Fibroblast growth factor mediates hypoxia-induced endothelin-- a receptor expression in lung artery smooth muscle cells. J Appl Physiol. 2003 Aug; 95(2):643-51; discussion 863. doi: 10.1152/japplphysiol.00652.2002. PMID:12851419
  19. Wang D, Oparil S, Feng JA, Li P, Perry G, Chen LB, Dai M, John SW, Chen YF. Effects of pressure overload on extracellular matrix expression in the heart of the atrial natriuretic peptide-null mouse. Hypertension. 2003 Jul; 42(1):88-95. doi: 10.1161/​01.HYP.0000074905.22908.A6. PMID:12756220