Sadeep Shrestha, PhD

Associate Professor
Ryals 217L

Dr. Shrestha received his MHS (Infectious disease/Genetic Epidemiology) and PhD (Genetic Epidemiology) from the Bloomberg School of Public Health, Johns Hopkins University and MS (Biotechnology) from Kreiger School of Arts and Sciences, Johns Hopkins University. He was a post-doctoral fellow at the Laboratory of Genomic Diversity, NCI-Frederick before joining the School of Public Health faculty in 2005. 

Dr. Shrestha is the director of the Epidemiology Phd Program. He also holds an appointment in the Minority Health Research Center, Center for AIDS Research and the Comprehensive Cancer Center at UAB, and Sparkman Center. He is also a faculty of Genetics and Genomic Sciences. He currently serves in the editorial board of Genes and Immunity, Human Immunology, and Kathmandu University Medical Journal and also served as associate editor of American Journal of Epidemiology from 2010-2013 . He is the recipient of the 2013 Graduate School Dean’s Award for Excellence in Mentorship.

Dr. Shrestha co-directs the Epidemiology Seminar Series and Journal Club.

Research Interests

Dr. Shrestha's research interests include epidemiology, infectogenomics, vaccinogenomics, pharmacogenetics, and immunogenetics of outcomes and sequelae of HIV, other viral infections and immune-related complications: 

HPV related outcomes and cancers

  •    Immunogenetics of HPV persistence/clearance - association studies in WIHS, REACH, HERS, ALTS & HIM cohorts
  •    Biomarkers of HPV-related pre-cancer disease progression - gene expression, genetic association
  •    Epidemiology of HPV and cervical cancer in Nepal -

Outcomes and complications in HIV-1 patients

  •    Acceleration and accentuation of atheroslcerosis - genetic associations in FRAM, WIHS and MACS cohorts
  •    Coinfections and comorbities related to HIV infection and HAART, especially in the context of host genetics

Kawasaki disease - KD Immunogenetic Consortium in collaborations with Seattle Children's Hospital and affiliated pediatric clinics in northwest US

  •   Susceptibility to KD (Trio-based family study)
  •    Differential response to IVIG treatment
  •    Development of coronary artery disease 


He is the course master for Epi 731 - Genetic Epidemiology & Epi 635 - Genetics in Public Health in SOPH (taught alternatively every other year), and GBS721 - Genetic Epidemiology in the School of Medicine. He also co-directs Basic Research in Infectious and Genetic Epidemiology (BRIDGE) program.



Publications in Pubmed

Curriculum Vitae: