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LINKAGE AND LINKAGE DISEQUILIBRIUM DATA ANALYSIS CLEARINGHOUSE

The Human Genome Project, the availability of millions of identified SNPs, and the initiation of the HapMap project greatly facilitate such studies and have stimulated the development of new methods of analyses of complex diseases and traits. It is difficult for applied investigators to keep up with, implement, and interpret the results obtained from these specialized methods. The UAB-HSF-GEF has sponsored the Linkage and Linkage Disequilibrium Data Analysis Clearinghouse (LDDAC) as a free service for all UAB investigators without grant support for association/linkage analysis of the complex diseases from March 1, 2004 until February 28, 2007. The Clearinghouse is housed in and staffed by members of the Section on Statistical Genetics in the Department of Biostatistics at The University of Alabama at Birmingham.

Our goal is to assist in the grant development, publication writing, planning, analysis, and interpretation of Linkage and Linkage Disequilibrium data for UAB investigators. We strive to provide the most statistically valid and reliable results and interpretation possible. We aim to increase the number of high quality association/linkage publications being authored by UAB investigators, to increase the funding for association/linkage, and make UAB a leader in deciphering the complex disease etiology.

Following are the category of programs we have available for the analysis: