2008 HALOTYPE CONFERENCE

Details and Registration Information:  pdf   MS Word

Overview:
The University of Alabama at Birmingham's Section on Statistical Genetics is very pleased to offer this NHGRI-funded Conference on Haplotype Analysis of Population & Pedigree Data in Association Studies. Haplotype analysis plays an important role in association studies but also poses great challenges to scientists with the availability of large number of dense SNP markers. This 2-day meeting will review the up-to-date methodological development of haplotype analysis and explore unanswered questions on how best to perform the haplotype analysis and to what extent and in what context the haplotype analysis can increase power for association studies. It is aimed at established investigators, post-doctoral fellows, and advanced graduate students. Women, members of underrepresented minority groups and individuals with disabilities are strongly encouraged to apply. .

Schedule of Events: Agenda

DATE	TIME	TOPIC	SPEAKER	Resource(s)
Wed 5/7/2008	8:00 - 8:30 am	Registration
	8:30 - 8:45 am	Welcome and Introduction	Kui Zhang, Ph.D. & David B. Allison, Ph.D., UAB
	Session I: Haplotype Inference from Unrelated Individuals
	8:45 - 8:50 am	Overview by Moderator	José R Fernández, Ph.D., UAB
	8:50 -9:25 am	Statistical methods for large-scale population genotype data and their application to haplotype inference	Matthew Stephens, Ph.D., Chicago University
	9:25 - 10:00 am	Haplotype analysis in the presence of informatively missing genotype data	Nianjun Liu, UAB
	10:00 - 10:15 am	Break
	10:15 - 10:50 am	Bayesian methods for haplotype inference from unrelated individuals	Zhaohui Qin, Ph.D., University of Michigan
	10:50 - 11:30 am	Panel and Discussion by Moderator	David B. Allison, Ph.D., UAB
	11:30 - 1:30 pm	Lunch
	Session II: Haplotype-based Association Methods from Unrelated Individuals
	1:30 - 1:35 pm	Overview by Moderator	Rui Feng, Ph.D., UAB
	1:35 - 2:10 pm	Likelihood-based inferences on haplotype-disease associations, with applications to untyped SNPs	Danyu Lin. Ph.D., University of North Carolina at Chapel Hill
	2:10 - 2:45 pm	Tree- and forest-based genomewide association analysis	Heping Zhang, Ph.D., Yale University
	2:45 - 3:00 pm	Break
	3:00 - 3:35 pm	A gene-trait similarity regression for haplotype analysis in genome-wide association studies	Jung-Ying Tzeng, Ph.D., North Carolina State University
	3:35 - 4:10 pm	Haplotype sharing for genome-wide case-control association studies	Glen Satten, Ph.D., Center for Disease Control
	4:10 - 4:50 pm	Panel and Discussion moderator by	Guimin Gao, Ph.D., UAB
	5:30 - 7:00 pm	Dinner
	7:00 - 9:00 pm	Debate Session: Is the haplotype analysis critical in genome wide association studies?	Con: Derek Gordon, Ph.D., Rutgers University [Slides] Pro: Daniel Schaid, Ph.D., Mayo Clinic Provocateur: Michael Province, Ph.D., Washington University St. Louis
DATE	TIME	TOPIC	SPEAKER	Resource(s)
Thu 5/8/2008	8:00 - 8:15 am	Welcome and Introduction	Guimin Gao, Ph.D & Hemant K. Tiwari, Ph.D., UAB
	Session III: Haplotype Inference from Pedigrees
	8:30 - 8:35 am	Overview by Moderator	Guimin Gao, Ph.D., UAB
	8:35 - 9:10 am	Challenges for haplotype inference from large pedigrees	Jeffrey O'Connell, Ph.D., University of Maryland
	9:10 -9:45 am	Computational methods for haplotype inference from general pedigrees	Jing Li, Ph.D., Case Western Reserve University
	9:45 - 10:15 am	Break
	10:15 -10:50 am	Statistical methods for haplotype inference from general pedigrees	Kui Zhang, Ph.D., University of Alabama at Birmingham
	10:50 -11:30 am	Panel and Discussion by Moderator	Hemant K.Tiwari, Ph.D., UAB
	11:30 - 1:30 pm	Lunch
	Session IV: Haplotype based association methods for pedigrees
	1:30 - 1:35 pm	Overview by Moderator	Nianjun Liu, Ph.D., UAB
	1:35 - 2:10 pm	An incomplete-data quasi-likelihood approach to case-Control haplotype	Mary Sara McPeek, Ph.D., The University of Chicago
	2:10 - 2:45 pm	The performance of imputation methods for haplotype analysis in large pedigrees	Tasha Fingerlin, Ph.D., University of Colorado at Denver
	2:45 - 3:00 pm	Break
	3:00 - 3:35 pm	Fast and efficient tests of association for untyped markers in case-control studies	Michael Epstein, Ph.D., Emory University
	3:35 - 4:15 pm	Panel and Discussion by moderator	Kui Zhang, Ph.D., UAB
	4:15 pm	Adjourn

UAB Faculty:

• David Allison, Ph.D.
• Rui Feng, Ph.D.
• José Fernandez, Ph.D.
• Guimin Gao, Ph.D.
• Nianjun Liu, Ph.D.
• Hemant Tiwari, Ph.D.
• Kui Zhang, Ph.D.

External Faculty:

• Michael Epstein, Ph.D., Emory University
• Tasha Fingerlin, Ph.D., University of Colorado at Denver
• Derek Gordon, Ph.D., Rutgers State University of New Jersey
• Jing Li, Ph.D., Case Western Reserve University
• Danyu Lin, Ph.D., University of North Carolina at Chapel Hill
• Mary Sara McPeek, Ph.D., The University of Chicago
• Jeffrey R. O'Connell, Ph.D., University of Maryland
• Michael Province, Ph.D., Washington University St. Louis
• Glen Satten, Ph.D., Centers for Disease Control and Prevention
• Daniel Schaid, Ph.D., Mayo Clinic
• Matthew Stephens, Ph.D., University of Chicago
• Zhaohui Qin, Ph.D., University of Michigan
• Jung-Ying Tzeng, Ph.D., North Carolina State University
• Heping Zhang, Ph.D., Yale University

Contact Information:

Logistics: Richard Sarver
Department of Biostatistics
1665 University Blvd, RPHB 414
University of Alabama at Birmingham
Birmingham, AL 35294-0022
Phone: (205) 975-9169
Email: rsarver@uab.edu

Scientific: Kui Zhang PhD
Department of Biostatistics
1665 University Blvd, RPHB 317D
University of Alabama at Birmingham
Birmingham, AL 35294-0022
Phone: (205) 996-4094
Email: KZhang@ms.soph.uab.edu

Funded by:

Sponsors:

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