4TH SHORT COURSE ON NEXT-GENERATION SEQUENCING: TECHNOLOGY AND STATISTICAL METHODS

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Details and Registration Information:  pdf   MS Word
Held On: Mon 12/15/14 – Thurs 12/18/14
Location:

University of Alabama at Birmingham
Heritage Hall – Lecture Room 104
1401 University Blvd.
Birmingham, AL 35233
http://www.uab.edu/map/hhb

Lodging: Doubletree Hotel by Hilton
808 South 20th Street
Birmingham, AL 35205
(205) 933-9000; fax: (205) 933-0920

SpringHill Suites by Marriott
2024 4th Avenue South
Birmingham, AL 35233
(205) 322-8600; fax: (205) 322-9915

Residence Inn by Marriott-UAB
821 20th Street South
Birmingham, AL 35205
(205) 731-9595; fax: (205) 731-9596

 

  • Overview
  • Faculty
  • Apply
  • Contact

Next-generation sequencing technology is impacting almost all aspects of biomedical research. This technology generates an unprecedented wealth of data that demands novel analysis strategies. While IT infrastructure and bioinformatics developments are obviously required to enable sound information extraction, sophisticated statistical methodologies and algorithms are also essential for interpreting the data. In this regard, we are organizing a NHGRI funded four-day short course, calling statisticians, genetic epidemiologists, bioinformaticians, and genome biologists, to discuss the statistical challenges and opportunities in next-generation sequencing data analysis. We believe that this course will provide a venue for exchanging of cutting-edge information and ideas, and fostering collaborations among methodologists, analysts, and biomedical investigators.

Schedule of Events: [PDF file]

**NOTE: You will need Microsoft Silverlight to view videos.

Mon 12/15/14 - UAB in Birmingham, AL
Time Topic Speaker Resource(s)
08:00 - 09:15 AM Registration - Heritage Hall, Room 125 Derry Crawford, MSHA  
09:15 - 09:30 AM Introductory Remarks Hemant Tiwari, PhD - UAB  
09:30 - 10:30 AM Technical Overview of NGS (Platforms; chemistry; library construction) Shawn Levy, PhD – HudsonAlpha Institute of Biotechnology Video
10:30 - 10:45 AM Discussion Shawn Levy, PhD  
10:45 - 11:00 AM BREAK
11:00 - 12:00 PM Next Generation Sequencing in Methylation Studies Devin Absher, PhD - HudsonAlpha Video
12:00 - 12:15 PM Discussion Devin Absher, PhD  
12:15 - 01:30 PM LUNCH BREAK
01:30 - 02:30 PM Predicting Causal Variation Greg Cooper, PhD - HudsonAlpha Video
02:30 - 02:45PM Discussion Greg Cooper, PhD  
02:45 - 03:00PM BREAK
03:00 - 04:00 PM StatGenLab, a virtual machine for genetic data analysis Jelai Wang, BSc – Wang Scientific Software Solutions, LLC  
04:00- 06:00 PM Software Demonstration & Hands-on Computing (R & Bioinformatics File Formats) Xiangqin Cui, PhD – UAB  
07:00- 09:00 PM Dinner/Social @ The Edge of Chaos – 4th Floor, Lister Hill Library Participants & Faculty  

Tue 12/16/14 - UAB in Birmingham, AL
Time Topic Speaker Resource(s)
09:30 - 10:30 AM Functional Genomics: Identifying and characterizing cis-regulatory sequences Dan Savic, PhD – HudsonAlpha Video
10:30 - 10:45 AM Discussion Dan Savic, PhD  
10:45 - 11:00 AM BREAK
11:00 - 12:00 PM Variant Calling & Assembly NGS Data Degui Zhi, PhD - UAB Video
12:00 - 12:15 AM Discussion Degui Zhi, PhD  
12:15 - 01:30 PM LUNCH BREAK
01:30- 02:30 PM Rare Variants Analysis Michael Wu, PhD - Fred Hutchinson Cancer Research Center Video
02:30- 02:45 PM Discussion Michael Wu, PhD  
02:45 - 03:00 PM BREAK
03:00- 06:00 PM Software Demonstration & Hands-on Computing (SKAT & NGS, Variant Calling) Michael Wu, PhD; Vinodh Srini, MS - UAB  

Wed 12/17/14 - UAB in Birmingham, AL
Time Topic Speaker Resource(s)
09:30 - 10:30 AM Transcriptome Analysis Using NGS Xiangqin Cui, PhD - UAB Video
10:30 - 10:45 AM Discussion Xiangqin Cui, PhD  
10:45 - 11:00 AM BREAK
11:00 - 12:00 PM ChiP-Seq Data Analysis Hao Wu, PhD - Emory University Video
12:00 - 12:15AM Discussion Hao Wu, PhD  
12:15 - 01:30 PM LUNCH BREAK
01:30 - 02:30 PM Analysis of whole-genome bisulfite sequencing data Karen Conneely, PhD - Emory University Video
02:30 - 02:45 PM Discussion Karen Conneely, PhD  
02:45 - 03:00 PM BREAK
03:00- 06:00 PM Software Demonstration & Hands-on Computing (ChIP-Seq, BSmooth  and DSS) Hao Wu, PhD; Karen Conneely, PhD  

Thu 12/18/14 - UAB in Birmingham, AL
Time Topic Speaker Resource(s)
09:30 - 10:30 AM Computational Methods for Cancer Genome Interpretation Emidio Capriotti, PhD – UAB Video
10:30 - 10:45 AM Discussion Emidio Capriotti, PhD  
10:45 - 11:00 AM BREAK
11:00 - 12:00 PM Statistical Methods for NGS Data Nicholas Schork, PhD - J. Craig Venter Institute Video
12:00 - 12:15 PM Discussion Nicholas Schork, PhD  
12:15- 01:30 PM LUNCH BREAK
01:30 - 02:30 PM 1000 Genomes & Beyond Fuli Yu, PhD - Baylor College of Medicine Video
02:30 - 02:45 PM Discussion Fuli Yu, PhD  
02:45 - 03:00 PM BREAK
03:00 - 04:00 PM Software Demonstration & Hands-on Computing (RNA-Seq) Degui Zhi, PhD  
04:00 PM Adjourn

 

UAB Faculty:

External Faculty:

Full List of Rotating Faculty can be found by Click here.

Apply

Application deadline:
Applications for 2014 NHGRI Short Course on Next Generation Sequencing will be accepted till Saturday November 15, 2014.

How to Apply

To apply, please perform the following tasks either via our website or by sending materials to statgenetics@uab.edu:

  1. Complete this application form (PDF or Word). Only fully completed application forms will be considered.
  2. Forward your current curriculum vitae.
  3. One page personal statement, explaining: why you are interested in attending this course, & how the course will aid your professional development, research, etc. Be sure to provide details of your background in Genetics, Statistics, etc.
  4. Computing background such as knowledge of R and UNIX commands is highly encouraged.

Attendance is limited.  Please apply prior to Sat 11/15/2014. Accepted applicants will be notified by Fri 11/21/2014, and applicants should make arrangements for payment of the registration fee by December 12th.

Women, members of underrepresented minority groups, and individuals with disabilities are strongly encouraged to apply.

Upon Acceptance, fee:
           $500 - academic, government, and non-profit organizations
           $2,500 - for-profit organizations

Acceptance includes course tuition, syllabus, and refreshment breaks.  Fee will be payable upon acceptance into the course.

Email your application, CV/resumes, and personal statement to: statgenetics@uab.edu

For more information, contact:
Derry Crawford, MSHA
Program Manager
UAB SOPH Department of Biostatistics
Section on Statistical Genetics
1665 Univ. Blvd, RPHB 414
Birmingham, AL 35294-0022
205.975.9298 T
205.975.2541 F
derry@uab.edu 

Contact Information:

Logistics: Derry Crawford
Department of Biostatistics
1665 University Blvd, RPHB 414
University of Alabama at Birmingham
Birmingham, AL 35294-0022
Phone: (205) 975-9298
Email: Statgenetics@uab.edu

Scientific: Hemant K Tiwari, PhD
Department of Biostatistics
1665 University Blvd, 420C
University of Alabama at Birmingham
Birmingham, AL 35294-0022
Phone: (205) 934-4907
Email: htiwari@uab.edu

 

Sponsors:  National Human Genome Research Institute
Section on Statistical Genetics, University of Alabama at Birmingham
HudsonAlpha


NHGRI Disclaimer: This material is based upon work supported by the National Human Genome Research Institute (NHGRI) under Grant No. R25HG006110. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the NHGRI.