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Details and Registration Information:  pdf   MS Word
Held On: Mon 12/16/13 – Thurs 12/19/13

Doubletree Hotel by Hilton
808 South 20th Street
Birmingham, AL 35205
(205) 933-9000; fax: (205) 933-0920

SpringHill Suites by Marriott
2024 4th Avenue South
Birmingham, AL 35233
(205) 322-8600; fax: (205) 322-9915


University of Alabama at Birmingham
Heritage Hall – Lecture Room 104
1401 University Blvd.
Birmingham, AL 35233


  • Overview
  • Faculty
  • Apply
  • Contact

Next-generation sequencing technology is impacting almost all aspects of biomedical research. This technology generates an unprecedented wealth of data that demands novel analysis strategies. While IT infrastructure and bioinformatics developments are obviously required to enable sound information extraction, sophisticated statistical methodologies and algorithms are also essential for interpreting the data. In this regard, we are organizing a NHGRI funded four-day short course, calling statisticians, genetic epidemiologists, bioinformaticians, and genome biologists, to discuss the statistical challenges and opportunities in next-generation sequencing data analysis. We believe that this course will provide a venue for exchanging of cutting-edge information and ideas, and fostering collaborations among methodologists, analysts, and biomedical investigators.

Schedule of Events: [PDF file]

Mon 12/16/13 - UAB in Birmingham, AL
Time Topic Speaker Resource(s)
08:00 - 08:45 AM Registration Derry Crawford, MSHA  
08:45 - 09:00 AM Introductory Remarks Hemant Tiwari, PhD - UAB  
09:00 - 10:00 AM Technical Overview of NGS (Platforms; chemistry; library construction) Shawn Levy, PhD – HudsonAlpha Institute of Biotechnology Video
10:00 - 10:15 AM Discussion Shawn Levy, PhD  
10:15 - 11:15 AM BREAK
11:15 - 12:15 PM Next Generation Sequencing for Epigenetic Analysis Devin Absher, PhD - HudsonAlpha Video
12:15 - 12:30 PM Discussion Devin Absher, PhD  
12:30 - 2:00 PM LUNCH BREAK
02:00 - 03:00 PM Annotation and Interpretation of Genetic Variation Greg Cooper, PhD - HudsonAlpha Video
03:00 - 03:15 PM Discussion Greg Cooper, PhD  
03:15 - 03:30 PM BREAK
03:30 - 04:30 PM Characterizing protein-DNA interactions through NGS Dan Savic, PhD - HudsonAlpha Video
04:30- 04:45 PM Discussion Dan Savic, PhD  

Tue 12/17/13 - UAB in Birmingham, AL
Time Topic Speaker Resource(s)
09:00 - 10:00 AM Rare Variants Analysis Michael Wu, PhD – UNC, Chapel Hill Video
10:00 - 10:15 AM Discussion Michael Wu, PhD  
10:15 - 10:30 AM BREAK
10:30 - 11:30 AM Variant Calling & Assembly NGS Data Degui Zhi, PhD - UAB Video
11:30 - 11:45 AM Discussion Degui Zhi, PhD  
11:45 - 01:15 PM LUNCH BREAK
01:15- 02:15 PM 1000 Genomes and Beyond Fuli Yu, PhD – Baylor College of Medicine Video
02:15- 02:30 PM Discussion Fuli Yu, PhD  
02:30 - 02:45 PM BREAK
03:00- 05:00 PM Software Demonstration (Exome & Whole Genome NGS) Degui Zhi, PhD; Michael Wu, PhD  
07:00 - 09:00 PM Dinner/Social @ The Edge of Chaos – 4th Floor Lister Hill Library

Wed 12/18/13 - UAB in Birmingham, AL
Time Topic Speaker Resource(s)
09:00 - 10:00 AM Transcriptome Analysis Xiangqin Cui, PhD - UAB Video
10:00 - 10:15 AM Discussion Xiangqin Cui, PhD  
10:15 - 10:30 AM BREAK
10:30 - 11:30AM ChiP-Seq Data Analysis Hao Wu, PhD – Emory University Video
11:30 - 11:45AM Discussion Hao Wu, PhD  
11:45 - 01:15 PM LUNCH BREAK
01:15 - 02:15 PM Bisulfite Sequencing Data Analysis of Epigenome Karen Conneely, PhD – Emory University Video
02:15 - 02:30 PM Discussion Karen Conneely, PhD  
02:30 - 02:45 PM BREAK
02:45- 03:45 PM Introduction to Galaxy David Crossman, PhD - UAB  
03:45- 04:00 PM Discussion David Crossman, PhD  
04:00 - 04:15 PM BREAK
04:15 - 06:00 PM Software Demonstration (ChiP-Seq, BS-Seq) Hao Wu, PhD; Karen Conneely, PhD  

Thu 12/19/13 - UAB in Birmingham, AL
Time Topic Speaker Resource(s)
09:00 - 10:00 AM Cloud Computing Jonas Almeida, PhD - UAB  
10:00 - 10:15 AM Discussion Jonas Almeida, PhD  
10:15 - 10:30 AM BREAK
10:30 - 11:30 AM Statistical Methods for NGS Data Nicholas Schork, PhD – Scripps Translational Science Institute Video
11:30 - 11:45 AM Discussion Nicholas Schork, PhD  
11:45- 01:15 PM LUNCH BREAK
01:15 - 04:00 PM Software Demonstration (RNA-Seq & Galaxy) Xiangqin Cui, PhD; David Crossman, PhD  
04:00 PM Adjourn


UAB Faculty:

External Faculty:

Full List of Rotating Faculty can be found by Click here.


Application deadline:
Applications for 2013 NHGRI Short Course on Next Generation Sequencing will be accepted till Saturday November 16, 2013.

How to Apply

To apply, please perform the following tasks either via our website or by sending materials to statgenetics@uab.edu:

  1. Complete this application form (PDF or Word).   Only fully completed application forms will be considered.
  2. Forward your current curriculum vitae.
  3. Also forward a brief statement detailing your background in Genetics, Statistics, etc.

Attendance is limited.  Please apply prior to Sat 11/16/2013. Accepted applicants will be notified by FriI 11/22/2013, and applicants should make arrangements for payment of the registration fee by December 13th, 2013.

Women, members of underrepresented minority groups, and individuals with disabilities are strongly encouraged to apply.

Upon Acceptance, fee:
           $500 - academic, government, and non-profit organizations
           $2,500 - for-profit organizations

Acceptance includes course tuition, syllabus, and refreshment breaks.  Fee will be payable upon acceptance into the course.

Email your application, CV/resumes, & background information to: statgenetics@uab.edu

For more information, contact:
Derry Crawford, MSHA
Program Manager
UAB SOPH Department of Biostatistics
Section on Statistical Genetics
1665 Univ. Blvd, RPHB 414
Birmingham, AL 35294-0022
205.975.9298 T
205.975.2541 F

Contact Information:

Logistics: Derry Crawford
Department of Biostatistics
1665 University Blvd, RPHB 414
University of Alabama at Birmingham
Birmingham, AL 35294-0022
Phone: (205) 975-9298
Email: Statgenetics@uab.edu

Scientific: Hemant K Tiwari, PhD
Department of Biostatistics
1665 University Blvd, 420C
University of Alabama at Birmingham
Birmingham, AL 35294-0022
Phone: (205) 934-4907
Email: htiwari@uab.edu


Sponsors:  National Human Genome Research Institute
Section on Statistical Genetics, University of Alabama at Birmingham

NHGRI Disclaimer:
This material is based upon work supported by the National Human Genome Research Institute (NHGRI) under Grant No. R25HG006110. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the NHGRI.

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