FIRST ANNUAL NSF-FUNDED SHORT COURSE ON STATISTICAL GENETICS & STATISTICAL GENOMICS

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Details and Registration Information:  pdf   MS Word

Held On: Mon 7/21/2008 - Fri 7/25/2008  
Location: Doubletree Hotel Birmingham
Heritage 2 Meeting Room
808 South 20th Street
Birmingham, AL 35205
(205) 933-9000; fax (205) 933-0920
When making your reservation, please identify yourself as with the "Statistical Genetics short course" group to receive the reduced room rate.
 

Overview:

Focusing on the analysis of complex traits characterized by quantitative variation, this five-day course will offer an interactive program to enhance researchers' ability to understand & use statistical genetic methods, as well as implement & interpret sophisticated genetic analyses. Including hands-on computer demonstrations and practice, the course will be useful to a wide range of investigators studying the genetics of plants, model organisms, livestock, wildlife, and humans, helping investigators to better understand, use, and, in some cases even undertake research on, statistical genetic methods. Statistical genetic methodology is critical to advancing basic biology which is, in turn, critical to fields like genetic epidemiology, evolutionary biology, ecology, pest management, marine biology, medicine, forestry, and agriculture.

Schedule of Events: Agenda

**NOTE: You will need RealPlayer to view videos.

DATE TIME TOPIC SPEAKER Resource(s)
Mon
7/21/2008
8:00 - 9:00 am Registration    
9:00 - 9:15 am Introductory Remarks Hemant K. Tiwari, Ph.D.  
9:15 - 10:00 am Discussion:  Interests & Expectations Participants  
10:00 -10:15 am Break    
10:15 - 12:00 pm Introduction to Biostatistics Warren Ewens, Ph.D. Notes, Slides
Video
10:15 - 12:00 pm Introduction to Genetics & Genomics Robert Elston, Ph.D. Video
12:00 - 1:30 pm Lunch    
1:30- 2:00 pm Case Control and Association Testing David B. Allison, Ph.D. Video
2:00- 3:15 pm The qualitative and the quantitative TDT (Transmission - Disequilibrium Test) Warren Ewens, Ph.D. Notes, Slides
Video
3:15 - 3:30 pm Break    
3:30 - 4:15 pm Structured Association Testing (SAT) David B. Allison, Ph.D. Video
4:15 - 5:00 pm Discussion All Faculty  
DATE TIME TOPIC SPEAKER Resource(s)
Tue
7/22/2008
8:00 - 9:00 am PLINK Tutorial Hemant K. Tiwari, Ph.D. Video
9:00 - 9:15 am Break    
9:15 - 10:30 am Haplotype Analysis in Association Studies Kui Zhang, Ph.D. Video
10:30 - 11:45 am Design of Microarray Experiments Guilherme Rosa, Ph.D Video
11:45 - 1:15 pm Lunch    
1:15 -2:30 pm Microarray: array types, quality control, and systems biology Grier Page, Ph.D. Video
2:30 - 2:45 pm Break    
2:45 - 4:00 pm Microarray Analysis: Inference Sandra Rodriquez-Zas, Ph.D. Video
4:00 - 5:15 pm Basic Experimental Cross QTL analysis Xiangqin Cui, Ph.D. Video
5:15 - 5:45 pm Discussion All Faculty  
DATE TIME TOPIC SPEAKER Resource(s)
Wed
7/23/2008
8:00 - 9:00 am Bioconductor Xiangqin Cui, Ph.D. Video
9:00 - 9:15 am Break    
9:15 - 10:30 am Bayesian Interval Mapping Brian Yandell, Ph.D. Video
10:30 - 11:45 am Bayesian Hierarchical Generalized Linear Models for QTL Analysis Nengjun Yi, Ph.D. Video
11:45 - 1:15 pm Lunch    
1:15 -2:30 pm Multivariate trait selection and estimation of multivariate fitness functions Bruce Walsh, Ph.D. Video
2:30 - 2:45 pm Break    
2:45 - 4:00 pm Whole Genome Enabled Marker Assisted Selection Guilherme Rosa, Ph.D. Video
4:00 - 5:15 pm Detecting selection using molecular signature -- Intra-specific approach Yunxin Fu, Ph.D. Video
5:15 - 5:45 pm Discussion All Faculty  
DATE TIME TOPIC SPEAKER Resource(s)
Thu
7/24/2008
8:00 - 9:00 am Software Demonstration (HDBSTAT, Power Atlas - Genomics Microarray) Jelai Wang Video
9:00 - 9:15 am Break    
9:15 - 10:30 am Methods, Examples, and Implications of Integrative Biology Atul Butte, Ph.D. Video
10:30 - 11:45 am Genome-Wide Association, Copy Number Variation and Biological Pathway Analysis Carl Langefeld, Ph.D. Video
11:45 - 1:15 pm Lunch    
1:15 -2:00 pm Discussion All Faculty  
3:00 - 6:00 pm R/qtlbim Software Demo Brian S. Yandell, PhD Video
Bayesian QTL mapping without tears Nengjun Yi, PhD Video
Software Demonstration: HAPLOVIEW and HAPLORE Kui Zhang, PhD Video
JMP Genomics Amit Patki Video
Ingenuity Systems Pathway Analysis (IPA) Kelly Vaughan, Ph.D. Video
6:00 - 7:00 pm Dinner    
7:00 - 9:00 pm Hands-on Faculty (Hemant K. Tiwari, Ph.D.)  
DATE TIME TOPIC SPEAKER Resource(s)
Fri
7/25/08
9:00 - 12:00 pm Roundtable Discussion Faculty (David B. Allison, Ph.D.)  

 

Software Hands-On: Participants Pre-read
To insure the depth and practicality of the training program, we will provide 10 laptops to students or student pairs in the classroom. Each computer will be loaded with statistical software including but not limited to SAGE, Mx, Genehunter, Genomic Control programs, STRUCTURE, Ancestry Map, SIMWALK, MERLIN, QTL Express, R/QTL, BQTL, Dandelion, HDBSTAT!, Bioconductor Suite, Phase and Arlequin (all freely available) as well as S-Plus, SPSS and SAS. Many of the faculty have substantial expertise with the use of software for statistical genetics and have even authored some. Please feel invited to bring your own laptop.

UAB Faculty:

External Faculty:

Full List of External Rotating Faculty can be found by Click here.

Contact Information:

Logistics: Richard Sarver
Department of Biostatistics
1665 University Blvd, RPHB 414
University of Alabama at Birmingham
Birmingham, AL 35294-0022
Phone: (205) 975-9169
Email: rsarver@uab.edu

Scientific: Hemant K Tiwari, PhD
Department of Biostatistics
1665 University Blvd, 420B
University of Alabama at Birmingham
Birmingham, AL 35294-0022
Phone: (205) 934-4907
Email: HTiwari@ms.soph.uab.edu

Funded by: National Science Foundation

Sponsors: SSG

Contributor: Genome Explorations

NSF Disclaimer:
This material is based upon work supported by the National Science Foundation under Grant No. (NSF MCB-0650606).
Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation.