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Kui Zhang, Ph.D.

Department of Biostatistics
Ryals Public Health Bldg, 317
University of Alabama at Birmingham
Birmingham, AL 35294
Phone: (205) 996-4094
Fax: (205) 975-2540
E-mail: kzhang@ms.soph.uab.edu

Full CV

 


Biography: Introduction for Dr. Kui Zhang and his research

Programs: Software packages developed by Kui Zhang's research group

Publications: Selected publications from Kui Zhang's research group

Teaching: A list of courses and their lecture notes

People: Members in Kui Zhang's research group
 

Biography


Dr. Kui Zhang obtained his PhD in probability and statistics from Peking University in 1999 and joined the section of statistical genetics of University of Alabama at Birmingham as a research assistant professor in 2003. He has two related but different research areas: (1) to develop a new methods and designing novel algorithms to locate complex disease genes in genetic linkage analysis and linkage disequilibrium analysis using both population-based and family-based data; (2) to develop computational tools to understand molecular functions combining different data such as gene expression microarray data and protein-protein interaction data. Currently, Dr. Zhang is continuing his methodology developments for linkage, disequilibrium, and haplotype analysis and microarray analysis. He is very interested in collaborating with other investigators to apply these methods to their projects.

For a detailed description of his research, please see his research statement (short version, full version)

For a detailed biography, please see his full CV and NIH Biosketch.

 

Programs

  • HapBlock: A set of dynamic programming algorithms for haplotype block partitioning and tag SNP selection using haplotype or genotype data
  • HAPLORE: A program for haplotype inference in general pedigrees without recombinants
  • HaploIHP: A program for haplotype inference for unrelated individuals using identified haplotypes and/or haplotype patterns.

Publications

  • Kui Zhang, Hongyu Zhao. 2000. Assessing Reliability of Gene Clusters from Gene Expression Data. Functional & Integrative Genomics 1:156-173. [PMID: 11793234]
     
  • Kui Zhang, Dayue Chen. 2001. The Probabilistic Study of d-SAT Problem. Advances in Mathematics (Chinese) 30: 231-237.
     
  • Shuanglin Zhang, Kui Zhang, Jinming Li, Hongyu Zhao. 2002. On a Family-based Haplotype Pattern Mining Method for Linkage Disequilibrium Mapping. The Proceeding of Pacific Symposium on Biocomputing 7:100-111. [PMID: 11928467]
     
  • Kui Zhang, Minghua Deng, Ting Chen, Michael S. Waterman, Fengzhu Sun. 2002. A Dynamical Programming Algorithm for Haplotype Block Partitioning. Proceedings of the National Academy of Sciences of the United States of America 99: 7335-7339. [PMID: 12032283]
     
  • Kui Zhang, Peter Calabrese, Magnus Nordborg, Fengzhu Sun. 2002. Haplotype Structure and Its Applications to Association Studies: Power and Study Designs. The American Journal of Human Genetics 71: 1386-1394. [PMID: 12439824]
     
  • Kui Zhang, Fengzhu Sun, Michael S. Waterman, Ting Chen. 2003. Haplotype Block Partitioning with Limited Resources and Applications to Human Chromosome 21 Haplotype Data. The American Journal of Human Genetics 73: 63-73. [PMID: 12802783]
     
  • Minghua Deng, Kui Zhang, Shipra Mehta, Ting Chen, Fengzhu Sun. 2003. Prediction of Protein Function Using Protein-protein Interaction Data. Journal of Computational Biology 10: 947-960. [PMID: 14980019]
     
  • Thomas G. Schulze, Kui Zhang, Yu-Sheng Chen, Nirmala Akula, Fengzhu Sun, Francis J. McMahon. 2004. Defining Haplotype Blocks and Tag Single-nucleotide Polymorphisms in the Human Genome. Human Molecular Genetics 35:335-342. [PMID: 14681300]
     
  • Kui Zhang, Zhaohui Qin, Jun Liu, Ting Chen, Michael S. Waterman, Fengzhu Sun. 2004. Haplotype Block Partitioning and Tag SNP Selection Using Genotype Data and Their Applications to Association Studies. Genome Research 14: 908-916. [PMID: 15078859]
     
  • Kui Zhang, Fengzhu Sun, Hongyu Zhao. 2005. HAPLORE: A Program for Haplotype Reconstruction in General Pedigrees without Recombination. Bioinformatics 21: 90-103. [PMID: 15231536]
     
  • Kui Zhang, Zhaohui Qin, Ting Chen, Jun Liu, Michael Waterman, Fengzhu Sun. 2005. HapBlock: Haplotype Block Partitioning and Tag SNP Selection Software Using A Set of Dynamic Programming Algorithms. Bioinformatics 21: 131-134. [PMID: 15333454]
     
  • T. Mark Beasley, Howard Wiener, Kui Zhang, Alfred A. Bartolucci, Christopher I. Amos, David Allison. 2005. Empirical Bayes Method for Incorporating Data from Multiple Genome Scans. Human Heredity 60: 36-42. [PMID: 16137992]
     
  • Kui Zhang, Fengzhu Sun. 2005. Assessing the Power of Tag SNPs in Mapping of Quantitative Trait Loci (QTL) with Extremal and Random Samples. BMC Genetics 6: 51. [PMID: 16236175]
     
  • Kui Zhang, Hongyu Zhao. 2006. A Comparison of Several Methods for Haplotype Frequency Estimation and Haplotype Reconstruction for Tightly Linked Markers from General Pedigrees. Genetic Epidemiology 30: 423-437. [PMID: 16685719]
     
  • Kui Zhang, Howard Wiener, Marker Beasley, Varghese George, Christopher I. Amos, David Allison. 2006. An Empirical Bayes Method for Analysis of Quantitative-Trait Loci from Multiple Genome Scans. Genetics 173: 2283-2296. [PMID: 16751667]
     
  • Yun Joo Yoo, Guimin Gao, Kui Zhang. 2007. Case-control association analysis of rheumatoid arthritis with candidate genes using related cases. BMC Proceeding 2007, 1(Suppl 1): S67. [PMID: 18466531].
     
  • Yun Joo Yoo, Jianming Tang, Richard A. Kaslow, Kui Zhang. 2007. Haplotype Inference for Present-absent Genotype Using Previously Identified Haplotypes and Haplotype Patterns. Bioinformatics 23: 2399-2406. [PMID: 17644820]
     

Teaching

People


Webpage last updated: May 01, 2009