A key source for collaboration across each of the projects will be the UAB Data Core. The Data Core will be housed in the UAB Pharmacoepidemiology and Economics Research (PEER) Group which is staffed by 15 statisticians with extensive experience conducting analyses for basic, clinical and population studies. The PEER unit provides data management and analytic support across UAB. The Data Core will hold monthly meetings with the principal investigators from each project. The Data Core will ensure synergy in data collection across projects, a shared analytic approach and facilitate the exchange of ideas for ancillary studies and hypothesis generating data analyses.